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  • Immunity

    Immunity
    av Dr Jenna Macciochi

    Pocket - 2020 - Engelska - ISBN: 9780008370268

    Start strengthening your immunity for good.

  • Oxford Handbook of Medical Statistics

    Oxford Handbook of Medical Statistics
    av Janet L. Peacock

    Häftad - 2020 - Engelska - ISBN: 9780198743583

    A good understanding of medical statistics is essential to evaluate medical research and to choose appropriate ways of implementing findings in clinical practice. The Oxford Handbook of Medical Statistics has been written to provide doctors and medi…

  • A Comprehensive and Practical Guide to Clinical Trials

    A Comprehensive and Practical Guide to Clinical Trials

    Häftad - 2017 - Engelska - ISBN: 9780128047293

    A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the compone…

  • A Practical Guide to Using Qualitative Research with Randomized Controlled Trials

    A Practical Guide to Using Qualitative Research with Randomized Controlled Trials
    av Alicia O'Cathain

    Häftad - 2018 - Engelska - ISBN: 9780198802082

    Researchers measure the effectiveness of new interventions using randomized controlled trials (RCTs). They are increasingly using qualitative research with these RCTs to explain the results of RCTs or facilitate the viability and efficiency of RCTs.…

  • Preventing and Treating Missing Data in Longitudinal Clinical Trials

    Preventing and Treating Missing Data in Longitudinal Clinical Trials
    av Craig H. Mallinckrodt

    Inbunden - 2013 - Engelska - ISBN: 9781107031388

    Recent decades have brought advances in statistical theory for missing data, which, combined with advances in computing ability, have allowed implementation of a wide array of analyses. In fact, so many methods are available that it can be difficult…

  • Preventing and Treating Missing Data in Longitudinal Clinical Trials

    Preventing and Treating Missing Data in Longitudinal Clinical Trials
    av Craig H. Mallinckrodt

    Häftad - 2013 - Engelska - ISBN: 9781107679153

    Recent decades have brought advances in statistical theory for missing data, which, combined with advances in computing ability, have allowed implementation of a wide array of analyses. In fact, so many methods are available that it can be difficult…

  • Controversial Statistical Issues in Clinical Trials

    Controversial Statistical Issues in Clinical Trials
    av Shein-Chung Chow

    Inbunden - 2011 - Engelska - ISBN: 9781439849613

    In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectiv…

  • Bayesian Designs for Phase I-II Clinical Trials

    Bayesian Designs for Phase I-II Clinical Trials
    av Ying Yuan

    Inbunden - 2016 - Engelska - ISBN: 9781498709552

    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into…

  • Evaluation of Drug Candidates for Preclinical Development

    Evaluation of Drug Candidates for Preclinical Development

    Inbunden - 2010 - Engelska - ISBN: 9780470044919

    Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive s…

  • Controlled Drug Delivery

    Controlled Drug Delivery

    Inbunden - 2019 - Engelska - ISBN: 9780367205560

    Published in 1983: Volume 2 deals with critical analyses of various test methodologies of polymeric implants, including their acute and chronic toxicological evaluation.

  • Global Clinical Trials

    Global Clinical Trials

    Häftad - 2016 - Engelska - ISBN: 9780128103555

    This book will explore the great opportunities and challenges which exist in conducting clinical trials in developing countries. By exploring the various regulations specific to the major players and providing insight into the logistical challenges…

  • Venoms to Drugs

    Venoms to Drugs

    Inbunden - 2015 - Engelska - ISBN: 9781849736633

    1. Gives an overview of the development of drugs from peptides and proteins present in venom.2. Six drugs derived from venoms have already been approved, and there are many more in development.3. Medicinal chemists, pharmacologists, poisons experts,…

  • Adverse Events

    Adverse Events
    av Jill A. Fisher

    Häftad - 2020 - Engelska - ISBN: 9781479862160

    Explores the social inequality of clinical drug testing and its effects on scientific results Imagine that you volunteer for the clinical trial of an experimental drug. The only direct benefit of participating is that you will receive up to $5,175.…

  • Innovative Statistics in Regulatory Science

    Innovative Statistics in Regulatory Science
    av Shein-Chung Chow

    Inbunden - 2019 - Engelska - ISBN: 9780367224769

    Statistical methods that are commonly used in the review and approval process of regulatory submissions are usually referred to as statistics in regulatory science or regulatory statistics. In a broader sense, statistics in regulatory science can be…

  • Conducting and Interpreting Clinical Trials in Heart Failure, An Issue of Heart Failure Clinics

    Conducting and Interpreting Clinical Trials in Heart Failure, An Issue of Heart Failure Clinics
    av Mona Fiuzat

    Inbunden - 2011 - Engelska - ISBN: 9781455711024

    This issue of Heart Failure Clinics is dedicated to an in-depth analysis of the conduct of clinical investigation in patients with acute decompensated heart failure (ADHF). It tackles the difficult questions involved in patient population, trial con…

  • Clinical Trials in Oncology, Third Edition

    Clinical Trials in Oncology, Third Edition
    av Stephanie Green

    Inbunden - 2012 - Engelska - ISBN: 9781439814482

    The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design,…

  • Sample Size Calculations in Clinical Research

    Sample Size Calculations in Clinical Research
    av Shein-Chung Chow

    Inbunden - 2017 - Engelska - ISBN: 9781138740983

    Praise for the Second Edition:"... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressiv…

  • Sample Size Calculations in Clinical Research

    Sample Size Calculations in Clinical Research
    av Shein-Chung Chow

    Häftad - 2020 - Engelska - ISBN: 9780367657765

    Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impress…

  • Clinical Trial Data Analysis Using R and SAS

    Clinical Trial Data Analysis Using R and SAS
    av Ding-Geng Chen

    Inbunden - 2017 - Engelska - ISBN: 9781498779524

    Review of the First Edition"The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and…

  • Handbook of Drug Screening

    Handbook of Drug Screening

    Inbunden - 2009 - Engelska - ISBN: 9781420061680

    Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively u…

  • Pharmaceutical Isothermal Calorimetry

    Pharmaceutical Isothermal Calorimetry
    av Simon Gaisford

    Inbunden - 2006 - Engelska - ISBN: 9780849331558

    Pharmaceutical Isothermal Calorimetry discusses the application of isothermal calorimetric techniques to challenges encountered during the rational design and development of novel drugs and drug delivery systems. Providing a comprehensive review of…

  • CRC Handbook of Sample Size Guidelines for Clinical Trials

    CRC Handbook of Sample Size Guidelines for Clinical Trials
    av Jonathan J. Shuster

    Inbunden - 2017 - Engelska - ISBN: 9781138105393

    The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables the researcher-with no b…

  • Clinical Trials

    Clinical Trials
    av Tom Brody

    Inbunden - 2011 - Engelska - ISBN: 9780123919113

    Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines is a practical guidebook for those engaged in clinical trial design. This book details the organizations and content of clinical trials, including trial…

  • Statistical Methods for Survival Trial Design

    Statistical Methods for Survival Trial Design
    av Jianrong Wu

    Inbunden - 2018 - Engelska - ISBN: 9781138033221

    Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint.T…

  • Useful and Harmful Interactions of Antibiotics

    Useful and Harmful Interactions of Antibiotics

    Inbunden - 2019 - Engelska - ISBN: 9780367234072

    First published in 1987: This book is intended as a guide for a very large group of practitioners in the medical, pharmaceutical, and biological fields. It will enable them to prescribe and use antibiotics in an improved way.

  • Bad Pharma How Medicine Is Broken, and How We Can Fix It

    Bad Pharma How Medicine Is Broken, and How We Can Fix It
    av Ben Goldacre

    Pocket - 2013 - Engelska - ISBN: 9780007498086

    'Bad Science' hilariously exposed the tricks that quacks and journalists use to distort science, becoming a 400,000 copy bestseller. Now Ben Goldacre puts the $600bn global pharmaceutical industry under the microscope. What he reveals is a fascinati…

  • Genomic Clinical Trials and Predictive Medicine

    Genomic Clinical Trials and Predictive Medicine
    av Richard M. Simon

    Inbunden - 2013 - Engelska - ISBN: 9781107008809

    Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable b…

  • Genomic Clinical Trials and Predictive Medicine

    Genomic Clinical Trials and Predictive Medicine
    av Richard M. Simon

    Häftad - 2013 - Engelska - ISBN: 9781107401358

    Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable b…

  • Chronopharmaceutics

    Chronopharmaceutics

    Inbunden - 2009 - Engelska - ISBN: 9780471743439

    Chronopharmaceutics covers the fundamentals of the various aspects of chronopharmaceutics in the fields of chronobiology, chronogenetics, chronophysiology, chronopathology, chronopharmacology, chronotherapeutics, chronotoxicology and chronobiotics,…

  • Statistical Design and Analysis of Clinical Trials

    Statistical Design and Analysis of Clinical Trials
    av Weichung Joe Shih

    Inbunden - 2015 - Engelska - ISBN: 9781482250497

    Statistical Design and Analysis of Clinical Trials: Principles and Methods concentrates on the biostatistics component of clinical trials. Developed from the authors' courses taught to public health and medical students, residents, and fellows durin…

  • Modern Dose-Finding Designs for Cancer Phase I Trials: Drug Combinations and Molecularly Targeted Agents

    Modern Dose-Finding Designs for Cancer Phase I Trials: Drug Combinations and Molecularly Targeted Agents
    av Akihiro Hirakawa

    Häftad - 2018 - Engelska - ISBN: 9784431555728

    This book deals with advanced methods for adaptive phase I dose-finding clinical trials for combination of two agents and molecularly targeted agents (MTAs) in oncology. It provides not only methodological aspects of the dose-finding methods, but al…

  • Envisioning a Transformed Clinical Trials Enterprise in the United States

    Envisioning a Transformed Clinical Trials Enterprise in the United States
    av Institute of Medicine

    Häftad - 2012 - Engelska - ISBN: 9780309253154

    There is growing recognition that the United States' clinical trials enterprise (CTE) faces great challenges. There is a gap between what is desired - where medical care is provided solely based on high quality evidence - and the reality - where the…

  • Analysis of Safety Data of Drug Trials

    Analysis of Safety Data of Drug Trials
    av Ton J. Cleophas

    Inbunden - 2019 - Engelska - ISBN: 9783030058036

    In 2010, the 5th edition of the textbook, "Statistics Applied to Clinical Studies", was published by Springer and since then has been widely distributed. The primary object of clinical trials of new drugs is to demonstrate efficacy rather than safet…

  • Randomized Phase II Cancer Clinical Trials

    Randomized Phase II Cancer Clinical Trials
    av Sin-Ho Jung

    Inbunden - 2013 - Engelska - ISBN: 9781439871850

    In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of ph…

  • An Insider's Guide to Clinical Trials

    An Insider's Guide to Clinical Trials
    av Curtis L Meinert

    Häftad - 2011 - Engelska - ISBN: 9780199742967

    Clinical trials receive a lot of media attention; we hear or read about them almost daily in reports heralding new and promising treatments or reports raising questions about the safety or efficacy of an established treatment. The randomized trial i…

  • Cluster Randomised Trials

    Cluster Randomised Trials
    av Richard J. Hayes

    Inbunden - 2017 - Engelska - ISBN: 9781498728225

    Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evalua…

  • Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

    Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
    av Gernot Wassmer

    Inbunden - 2016 - Engelska - ISBN: 9783319325606

    This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed…

  • Clinical Issues and Affirmative Treatment with Transgender Clients, An Issue of Psychiatric Clinics of North America

    Clinical Issues and Affirmative Treatment with Transgender Clients, An Issue of Psychiatric Clinics of North America
    av Lynne Carroll

    Inbunden - 2017 - Engelska - ISBN: 9780323509855

    This issue of the Psychiatric Clinics of North America will review Clinical issues and Affirmative Treatments with Transgendered Clients. Edited by Lynne Carroll and lore m. dickey, subjects discussed in the text include, but are not limited to, Ass…

  • Pregnancy and the Pharmaceutical Industry

    Pregnancy and the Pharmaceutical Industry
    av Kristine E. Shields

    Häftad - 2019 - Engelska - ISBN: 9780128185506

    Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and…

  • Clinical Trials Moving Towards Online Solutions

    Clinical Trials Moving Towards Online Solutions
    av Eduard Gringinger

    Häftad - 2008 - Engelska - ISBN: 9783836480536

  • Methods and Applications of Statistics in Clinical Trials, Volume 1 and Volume 2

    Methods and Applications of Statistics in Clinical Trials, Volume 1 and Volume 2
    av N. Balakrishnan

    Inbunden - 2014 - Engelska - ISBN: 9781118790786

    This set includes Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs & Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods. Volu…

  • Clinical Simulation in Medicine

    Clinical Simulation in Medicine
    av Poonam Malhotra Kapoor

    Inbunden - 2016 - Engelska - ISBN: 9789351525639

    Clinical simulations are practical learning experiences designed to give students exposure to a comprehensive range of clinical scenarios that may be encountered in the workplace.This book is a comprehensive reference guide to clinical simulations i…

  • Design and Analysis of Clinical Trials with Time-to-Event Endpoints

    Design and Analysis of Clinical Trials with Time-to-Event Endpoints

    Häftad - 2018 - Engelska - ISBN: 9781138372665

    Using time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or "noninformativeness" of the censoring mechanisms relative to the event. D…

  • Design and Analysis of Clinical Trials with Time-to-Event Endpoints

    Design and Analysis of Clinical Trials with Time-to-Event Endpoints

    Inbunden - 2009 - Engelska - ISBN: 9781420066395

    Using time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or "noninformativeness" of the censoring mechanisms relative to the event. D…

  • Group Work With Populations at Risk

    Group Work With Populations at Risk

    Häftad - 2010 - Engelska - ISBN: 9780195398564

    Group Work With Populations at Risk, Third Edition is a fundamental resource for practitioners in health and mental health settings and a comprehensive guidebook of group work skills. Geared toward students and professionals gaining a beginning unde…

  • Applied Meta-Analysis with R and Stata

    Applied Meta-Analysis with R and Stata
    av Ding-Geng Chen

    Inbunden - 2021 - Engelska - ISBN: 9780367183837

    Review of the First Edition:The authors strive to reduce theory to a minimum, which makes it a self-learning text that is comprehensible for biologists, physicians, etc. who lack an advanced mathematics background. Unlike in many other textbooks, R…

  • Estimands, Estimators and Sensitivity Analysis in Clinical Trials

    Estimands, Estimators and Sensitivity Analysis in Clinical Trials
    av Craig Mallinckrodt

    Inbunden - 2020 - Engelska - ISBN: 9781138592506

    The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plan…

  • How to Be Successful as a Consulting Biostatistician in Industry

    How to Be Successful as a Consulting Biostatistician in Industry
    av Peter Mesenbrink

    Inbunden - 2021 - Engelska - ISBN: 9781498753159

    This book provides guidance to the statisticians in industry on the non-technical "soft" skills that one needs to have in order to be successful as a statistician from the first day on the job until the last day. Focus is on oral and written communi…

  • Die Mistel in der Tumortherapie 4

    Die Mistel in der Tumortherapie 4

    Häftad - 2017 - ISBN: 9783945150689

  • Fundamental Concepts for New Clinical Trialists

    Fundamental Concepts for New Clinical Trialists
    av Scott Evans

    Inbunden - 2015 - Engelska - ISBN: 9781420090871

    Fundamental Concepts for New Clinical Trialists describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspects of trials not typically discussed in statistical methodol…

  • Fundamental Concepts for New Clinical Trialists

    Fundamental Concepts for New Clinical Trialists
    av Scott Evans

    Häftad - 2021 - Engelska - ISBN: 9780367783396

    Fundamental Concepts for New Clinical Trialists describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspects of trials not typically discussed in statistical methodol…

  • Clinical Trials

    Clinical Trials
    av Steven Piantadosi

    Inbunden - 2017 - Engelska - ISBN: 9781118959206

    Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on…

  • Design and Analysis of Quality of Life Studies in Clinical Trials

    Design and Analysis of Quality of Life Studies in Clinical Trials
    av Diane L. Fairclough

    Inbunden - 2010 - Engelska - ISBN: 9781420061178

    Design Principles and Analysis Techniques for HRQoL Clinical Trials SAS, R, and SPSS examples realistically show how to implement methodsFocusing on longitudinal studies, Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edit…

  • Lead Generation Approaches in Drug Discovery

    Lead Generation Approaches in Drug Discovery
    av Zoran Rankovic

    Inbunden - 2010 - Engelska - ISBN: 9780470257616

    This resource provides an integrated and comprehensive overview ofmodern approaches to drug lead discovery. Each chapter in this bookreviews the theoretical background and application of a keytechnology in drug discovery, complemented by relevant ca…

  • Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials

    Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials
    av Mark Chang

    Inbunden - 2019 - Engelska - ISBN: 9780815379447

    "This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow stati…